Researchers turn Salmonella into anti-viral gene therapy agent

UC Berkeley researchers have converted Salmonella bacteria from a foodborne pathogen into a safe delivery vehicle for anti-viral agents. They inserted virus-stopping ribozymes into Salmonella that had their ability to cause disease disabled, and then used the bacteria to effectively treat mice infected with cytomegalovirus. It is the first time bacteria have been successfully engineered to treat a viral infection.

A 411 on water’s next drop

The Berkeley-based student project NextDrop uses mobile phones to alert residents in developing countries when water is flowing in their neighborhood’s notoriously unreliable taps. NextDrop, co-winner of last year’s Big Ideas contest on campus, began a pilot study last summer in the south India city of Hubli.

Kepler telescope discovers six planets around distant star

UC Berkeley astronomer Geoffrey Marcy is among Kepler team members who have announced hundreds of new planet candidates discovered by the space telescope. Among the confirmed planets are six orbiting a star dubbed Kepler-11. This is the largest number of planets around any star besides the Sun.

Bread mold genomes demo 'reverse-ecology'

In a demonstration of “reverse-ecology,” UC Berkeley biologists have shown that one can determine an organism’s adaptive traits by looking first at its genome and checking for variations across a population. The study offers a powerful new tool in evolutionary genetics research, one that could be used to help monitor the effects of climate change and habitat destruction.

Cow rumen yields enzyme bonanza

Sequencing of microbes in the rumen of the cow has turned up a treasure trove of new enzymes that degrade tough plant material, providing new avenues for research to boost biofuel production from plants. The research, funded by the Energy Biosciences Institute, involves UC Berkeley chemical engineer Doug Clark and colleagues at LBNL and the Joint Genome Institue.

Chemist Gabor Somorjai awarded frontiers of knowledge prize

University Professor of Chemistry Gabor Somorjai has been awarded the 3rd annual BBVA Foundation Frontiers of Knowledge Award. Accompanied by a $550,000 prize, the award by the Spanish foundation honors Somorjai’s “pioneering experimental and conceptual contributions to the understanding of surface chemistry and catalysis at a microscopic and molecular level.