Conducts research in functional genomics, specializing in the fabrication, use, and analysis of DNA microarrays for large-scale gene expression profiling and genetic profiling, and providing full services for Affymetrix GeneChip arrays and Agilent DNA microarrays.
The High-Throughput Screening Facility (HTSF), located in the Li Ka Shing Center for Biomedical and Health Sciences, provides access to cell culturing space, automated liquid handling, automated plate reader and high-throughput, high-content microscopy instrumentation for screening experiments, along with tools for analysis and data visualization. Emphasis is on whole genome and sub-library siRNA screening from various sources but other high-throughput fluidics projects are welcome.
Provides massively parallel DNA sequencing on Illumina's HiSeq2500/2000 platforms and on Ion Torrent's Proton System, MiSeq sequencing, Illumina Array Services on the HiScan, and Biospecimen processing. Additional services include Illumina or Ion Torrent compatible Library Preparations, and quality control services including the Qubit, Bioanalyzer, and qPCR assay.
Serves all UC affiliated laboratories, government agencies and businesses providing Sanger sequencing, genotyping, high-throughput nucleic acid purification/quantification, PCR reaction cleanup, PCR products size selection, human cell line authentication, and free consultation services. Open access instruments include: BioRad CFX96 Touch Real Time PCR system, BioRad QX200 Droplet Digital PCR System, and 150L New Brunswick BioFlo Fermentor.