Research Expertise and Interest
genomics, genetics, computational biology, structural variation, RNA, diversity, aging, population genetics
The Sudmant Lab uses computational, statistical, and experimental methods to interrogate genetic and molecular phenotypic diversity at both the organismal and cellular level. Our lab studies the evolution of aging, and the evolution of genome structure. Our work in aging focuses on the the causes and consequences of stress and aging in organisms with a focus on post-transcriptional gene regulation, somatic mutation, and genetic adaption in long (and short) lived species. Our work in genome structure focuses on using state-of-the-art long read sequencing approaches to identify structural genetic diversity associated with both recent and long-term adaptations in humans and our closely related primate relatives.