Matthew B. Francis

Research Bio

Matthew Francis is a Professor in the Department of Chemistry. Research in the Francis group is focused on the development of new synthetic methods for site-specific protein modification. These new reactions are then applied to the construction of protein-based materials with useful optical and therapeutic functions. Current areas of research include (1) the development of nanoscale carriers for drug molecules and imaging agents using chemically modified viral capsids, (2) the generation of artificial light harvesting systems using the tobacco mosaic virus capsid, (3) the synthesis of new materials for the removal of heavy metals from water using metallothionein-polymer conjugates, and (4) the attachment of living cells to device surfaces through DNA-based adhesion.

Research Expertise and Interest

materials chemistry, drug delivery, organic chemistry, Protein modification, artificial photosynthesis, water purification

In the News

Berkeley startup aims to be a game changer in autoimmune disease therapy

Berkley startup, Catena Biosciences, is valued at over $10 million and stands as an example of Berkeley’s change-making spirt: Put entrepreneurial scientists, mission-driven business experts and accomplished faculty in the same space — focused on solving the world’s problems — and innovation will flourish.

Teaching

Courses taught during the three most recent semesters
2026 Spring 2025 Fall

  • Bioorganic Chemistry and Advanced Chemical Biology   [CHEM 136 - 001]   

  • Bioorganic Chemistry and Advanced Chemical Biology   [CHEM 236 - 001]   

  • Seminars for Graduate Students   [CHEM 298 - 027]   

  • Research for Graduate Students   [CHEM 299 - 023]   

  • Professional Preparation: Supervised Teaching of Chemistry   [CHEM 300 - 016]   

2025 Summer 2025 Spring

For additional information, please consult the UC Berkeley course schedule.