Jasper Rine

Jasper Rine

Title
Professor of the Graduate School
Department
Dept of Molecular & Cell Biology
Phone
(510) 642-7047
Fax
(510) 642-6420
Research Expertise and Interest
biology, cell biology, DNA replication, gene regulation, saccharomyces cerevisiae, genetic analysis, genome, cholesterol biosynthetic pathway, modification of proteins, prenylated proteins
Research Description

Jasper Rine is a Howard Hughes Medical Institute Professor and Professor of the Graduate School Division of Genetics, Genomics, Evolution, and Development.  The research in his lab is focused on the yeast Saccharomyces cerevisiae in which they use genetic analysis to explore issues of gene regulation and cell biology. In addition, they are developing genomic-based approaches to the study of cells by parallel analysis of the expression of all genes simultaneously. Their goal is to create a new kind of genetic analysis in which the genome is used as the unit of function, rather than individual genes or proteins. The gene regulation work focuses on the coupling between certain origins of DNA replication and the establishment of domains with different transcriptional states. The cell biology work focuses on the regulation of the cholesterol biosynthetic pathway and the roles intermediates of this pathway play in the covalent modification of numerous proteins including the Ras oncoprotein and in the trafficking of prenylated proteins.

In the News

March 31, 2011

Tata Consultancy partners with campus to interpret personal genomic variation

Thanks to initial funding from the India-based Tata Consultancy Services, the Center for Computational Biology has launched a pioneering initiative to develop a software platform to analyze differences in people’s genomes and bring closer the day when one’s personal genome will be a starting point for health and medical advice.

August 12, 2010

UC Berkeley alters DNA testing program

The California Department of Public Health has instructed the University of California, Berkeley, not to proceed with a portion of its ground-breaking program to educate students about genetic testing and personalized medicine.

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In the News

March 31, 2011

Tata Consultancy partners with campus to interpret personal genomic variation

Thanks to initial funding from the India-based Tata Consultancy Services, the Center for Computational Biology has launched a pioneering initiative to develop a software platform to analyze differences in people’s genomes and bring closer the day when one’s personal genome will be a starting point for health and medical advice.

August 12, 2010

UC Berkeley alters DNA testing program

The California Department of Public Health has instructed the University of California, Berkeley, not to proceed with a portion of its ground-breaking program to educate students about genetic testing and personalized medicine.

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