Andreas Stahl

Andreas Stahl

Title
Professor
Department
Dept of Nutritional Sciences & Toxicology
Phone
(510) 642-6900
Research Expertise and Interest
metabolism, obesity, adipose tissue, brown fat, thermogenesis, tissue engineering, diabetes, fatty acid transport, fatty acid, stem cells
Research Description

The overarching goal of our laboratory is to advance human health by re-engineer lipid fluxes in the context of obesity-related disorders to protect certain tissues, such as the liver, from detrimental effects of ectopic lipid deposition and to generate metabolically highly active tissues that can serve as a save destination for excess fatty acids. To this end, we are investigating molecular mechanisms governing lipid uptake, particularly for fatty acids and CoQ, hepatobiliary diseases, and adipocyte biology. Toward the later, we have been working on novel bioengineering based approaches to expand and activate brown adipose tissue. Further, to facilitate the assessment of altered nutrient fluxes, we have been developing and testing novel bioluminescent imaging approaches to quantitatively assess macro- and micronutrients in vivo and have been working as part of a multidisciplinary team toward modeling human metabolic function and disease using iPSC derived microphysiological devices, aka organs on a chip, for adipocytes, hepatocytes, and islets.

In the News

July 5, 2017

Smelling your food makes you fat

Our sense of smell is key to the enjoyment of food, so it may be no surprise that in experiments at the University of California, Berkeley, obese mice who lost their sense of smell also lost weight.
August 20, 2015

Engineered hot fat implants reduce weight gain in mice

Scientists at UC Berkeley have developed a novel way to engineer the growth and expansion of energy-burning “good” fat, and then found that this fat helped reduce weight gain and lower blood glucose levels in mice.