Research Expertise and Interest

nuclear receptor molecular biology, gene regulation

Research Description

David Moore is a professor in the Department of Nutritional Sciences and Toxicology.  The Moore laboratory studies the diverse functions of the nuclear hormone receptors in a variety of mouse models of human disease. We have a particular focus on the roles of diverse nuclear receptors in normal and diseased liver and gut. Their areas of interest include regulation of basic metabolism and its dysregulation in the metabolic syndrome and diabetes, as well as the impact of nuclear receptors in hepatocellular carcinoma, cholestasis, fibrosis and inflammatory bowel diseases.