Yang Dan

Research Bio

Yang Dan is a Professor of Neurobiology.  Her research lab aims to elucidate (1) what circuits in the mammalian brain control sleep, and (2) mechanisms by which the frontal cortex exerts top-down executive control. They use a variety of techniques, including optogenetics, electrophysiology, imaging, and virus-mediated circuit tracing.

Current Projects

Neural circuits controlling sleep. Using optogenetic manipulation, optrode recording, and cell-type-specific calcium imaging, they identify neuronal types that play critical roles in the generation of rapid-eye-movement (REM) sleep and non-REM sleep. Local synaptic interactions between cell types are measured by recordings in brain slices, and long-range connections are mapped using a variety of viral tools.

Function of the prefrontal cortex (PFC). Combining electrophysiological recording, calcium imaging, and optogenetic manipulation in mice performing PFC-dependent tasks, they aim to understand how the PFC generate task-related activity, and how the activity regulates the downstream targets for optimal behavioral control.

Research Expertise and Interest

neuronal circuits, mammalian visual system, electrophysiological, imaging, prefrontal cortex, sleep

In the News

Loading Class list ...