Research Expertise and Interest
genomics, biophysical, bioanalytical, physical chemistry, laser spectroscopy, resonance Raman, excited-state reaction dynamics photoactive proteins, rhodopsins, microfabricated chemical biochemical analysis devices, forensics, infectious disease detection
Research Description
Physical, Biophysical and Bioanalytical Chemistry — Richard Mathies has developed a variety of modern laser-based spectroscopic techniques to study excited-state reaction dynamics in photoactive proteins and to develop novel microfabricated chemical and biochemical analysis devices for terrestrial and extra-terrestrial applications.
Ultrafast Vibrational Spectroscopy of Reaction Dynamics. Mathies has used resonance Raman vibrational spectroscopy to study photochemical reaction dynamics of energy and information transducing systems especially the primary photochemistry of rhodopsins. Most recently his group developed the novel technique of Femtosecond Stimulated Raman Spectroscopy or FSRS that enables the acquisition of femtosecond time-resolved vibrational structure snapshots of reacting molecules.
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