Research Bio

James Nuñez is a molecular biologist whose research explores genome engineering, epigenetics, and gene regulation in human cells. He is best known for developing CRISPR-based technologies to study and manipulate chromatin, including tools for targeted epigenome editing. Nuñez’s work integrates molecular biology, genomics, genetics, and synthetic biology to investigate how chromatin structure and modifications regulate gene expression and cellular identity. His research contributes to the development of precision genome engineering technologies for biomedical applications and as potential therapeutic platforms for treating and managing diseases.

He is an Assistant Professor of Molecular and Cell Biology at UC Berkeley and an Investigator of the Chan Zuckerberg Biohub San Francisco. Nuñez has been recognized as a Hanna Gray Fellow of HHMI, a Pew Biomedical Scholar, a Sloan Research Fellow, and a Vallee Foundation Scholar.

Research Expertise and Interest

genetics, epigenetics, CRISPR-based genome and epigenome editing