Ian Holmes

Research Bio

Ian Holmes is a professor in the Bioengineering department and the holder of the Dr. Richard Carl Dehmel Distinguished Professorship (2026-2031). He is affiliated with the Bioengineering and Computational Precision Health bicampus (UCSF-Berkeley) PhD programs, as well as the Computational Biology and Biophysics PhD programs at UC Berkeley.

The Holmes Lab brings techniques from machine learning, statistical linguistics, phylogenetics, and web development to bear on the interpretation and analysis of genomic data. Particular areas of interest include the development of basecalling and analysis software for nanopore sequencing; phylogenetic reconstruction using Bayesian approaches; the use of deep learning to predict and design protein structures; and the development of modern machine learning-backed web user interfaces to maximize the scientific utility of genome sequence data.

Research Expertise and Interest

computational biology, molecular evolution, computational genomics, Systems and Synthetic Biology

Teaching

Courses taught during the three most recent semesters
2026 Fall 2026 Summer 2026 Spring
  • Probabilistic Modeling in Computational Biology   [BIOENG 241]  [LEC 001]  [LAB 101]   

  • Individual Study or Research   [BIOENG 299 - 012]   

2025 Fall