The Robey Lab is interested in how signaling pathways control cell fate decisions. By using T cell development and immune responses in the mouse as model systems, they can take advantage of the powerful genetic approaches available in the mouse, while learning about a mammalian immune system that is very close to our own. The lab also makes extensive use of 2-photon imaging approaches to observe and analyze T cell behavior in real-time in situ.
Research Expertise and Interest
fate determination in the T-lymphocyte lineage, T cell development in the mouse, thymic development, cellular maturation, parasitic infection, chronic infection, host-pathogen interactions, Toxoplasma gondii