Research Bio

David D. Moore is a molecular metabolic biologist whose work has defined how nuclear hormone receptors regulate liver physiology and whole-body energy homeostasis. His laboratory has uncovered fundamental mechanisms by which nuclear hormone receptors coordinate transcriptional, translational, and organelle-level programs that govern lipid metabolism, fasting responses, xenobiotic detoxification, and proteostasis. His research spans molecular biology, metabolic physiology, and systems approaches to reveal how dietary and environmental inputs remodel hepatic function, with major implications for obesity, diabetes and metabolic liver disease.

Moore is Professor of Nutritional Sciences and Toxicology and mentors students and trainees across metabolism, gene regulation, and translational bioscience. He is an elected member of the National Academy of Sciences and a Fellow of the American Association for the Advancement of Science.

Research Expertise and Interest

nuclear receptor molecular biology, gene regulation