Research Expertise and Interest
optometry, vision science, myopia, refractive errors, accommodation, aberrations, eye growth, ocular therapeutics, optical myopia control, pharmacological myopia control, ocular tissue engineering, ocular stem cells
Christine Wildsoet is a professor of Optometry and Vision Science. The research at Wildsoet Lab is largely focused on refractive error development and myopia (short-sightedness). Cell and tissue cultures, as well as animal models (chicks and guinea pigs), and humans are used on on-going basic and clinical translational research directed towards:
- Understanding eye growth regulation and myopia, including the local ocular signal pathways linking the retina (seeing layer) with the outer support structures, i.e., choroidal and scleral components of the eye wall, the role of the retinal pigment epithelium as a cellular relay, key changes in choroid and sclera underlying listened growth, and the role of intraocular pressure as a potential inflationary force.
- Understanding mechanisms underlying currently used clinical myopia control strategies, including optical and pharmacological interventions, wiht a view to improving efficacy, as well as developing novel approaches, including gene therapy- and tissue engineering-based ones.
- Understanding the current myopia epidemic and specifically the underlying visual and behavioral factors that drive myopia, with a view to developing behavioral interventions to protect against myopia.