The major research efforts of my laboratory are in the area of biochemical nutrition and, in particular, the control of one carbon metabolism. We investigate experimental nutrition problems at a basic molecular or cellular level to obtain a better understanding of factors that influence nutritional requirements and how this varies among the population. We study how genetic variation in the pathways of one carbon metabolism influence chronic disease risk and susceptibility to birth defects using humans and genetically modified animal models.
Research Expertise and Interest
health and nutrition, nutritional sciences and toxicology, birth defects, nutritional genomics