Research Bio
A single genome produces the huge diversity of cells and tissues needed to make a human by regulating gene expression to turn on and off the right genes at the right times. The final, post-transcriptional steps of gene expression — RNA processing and translation — are essential to the proper outcome. Our goal is to understand how these layers of regulation are encoded in gene sequences and how disruptions to this regulation can cause disease. Our research uses machine learning and other computational methods, coupled with high-throughput experiments, to understand how post-transcriptional regulation leads to robust and flexible control of gene expression.
Research Expertise and Interest
computational biology, molecular biology
In the News
2025 MTI Innovator Awardees Announced
Chan Zuckerberg Biohub Awards $21 Million to 21 Berkeley Researchers
Teaching
Individual Study or Research [BIOENG 299 - 026]
Computational Functional Genomics [BIOENG C149 - 001]
Computational Functional Genomics [BIOENG C249 - 001]
Introduction to Research in Computational Biology [CMPBIO 294A - 001]
Computational Functional Genomics [CMPBIO C149 - 001]
Computational Functional Genomics [CMPBIO C249 - 001]
Scientific Communication and Experimental Rigor Graduate Seminar [MCELLBI 287 - 262]
Research [MCELLBI 292 - 262]
Individual Study or Research [BIOENG 299 - 025]
Introduction to Machine Learning for Computational Biology [BIOENG 145 - 001]
Introduction to Machine Learning for Computational Biology [BIOENG 245 - 001]
Individual Study or Research [BIOENG 299 - 016]
Research Review in Genetics and Development: RNA Systems Biology [MCELLBI 249I - 001]
Research [MCELLBI 292 - 262]
Individual Study or Research [BIOENG 299 - 026]
Computational Functional Genomics [BIOENG C149 - 001]
Computational Functional Genomics [BIOENG C249 - 001]
Introduction to Research in Computational Biology [CMPBIO 294A - 001]
Computational Functional Genomics [CMPBIO C149 - 001]
Computational Functional Genomics [CMPBIO C249 - 001]
Research Review in Genetics and Development: RNA Systems Biology [MCELLBI 249I - 001]
Graduate Seminar [MCELLBI 290 - C02]
Research [MCELLBI 292 - 262]