Research interests concern pathogenic mechanisms of biological agents that cause infectious disease. The focus of this research is to understand the basis of immunity, pathogenesis, and virulence of the obligate intracellular pathogen Chlamydia. The genetic basis of chlamydial developmental regulation is studied at the level of macromolecular chromosomal organization and mechanisms of developmental-stage specific transcription. The molecular interactions of the parasite and the host are defined both in the context of specific microbe-cell interactions and in relation to host immune responses.
Research Expertise and Interest
molecular genetics, microbiology, infectious disease, pathogenesis