We are constructing an integration vector--a plasmid that can insert in the B. anthracis chromosome--that will allow us to express particular antigens of B. anthracis at a high level. The new phages that we are characterizing are extremely virulent. We intend to determine why this is so.
Research Expertise and Interest
listeria monocytogenes, phage-based integration vector, Bacillus anthracis, vaccine