Professor of Virology
School of Public Health
buehring@berkeley.edu
510-642-3870

Research Expertise and Interest

public health, use of cells in breast fluids for diagnostic purposes, viruses and human cancer, role of bovine leukemia virus in causing human breast cancer

Description

Gertrude C. Buehring, Ph.D. is a professor of virology in the Infectious Diseases and Vaccinology Division of the School of Public Health at the University of California, Berkeley. Her research goal is to uncover a viral agent of breast cancer, and for the past 20 years she has been pursuing bovine leukemia virus (BLV) as a suspect. This virus causes widespread infection in cattle and is harbored within their milk and blood cells. Breast cancer incidence is highest in countries with the greatest consumption of milk and dairy products. Her research group has made several important discoveries about BLV that support its plausibility as a breast cancer virus: It infects the breast epithelium of cattle (it was previously thought to infect only lymphocytes); it is hormone responsive; and it inhibits DNA repair, which may be its mechanism of transforming cells from normal to malignant. Her group also established that ≈40% of humans have antibodies to BLV, and that BLV DNA is present in breast tissue and significantly associated with breast cancer.

She has received several honorary awards for her research including the Cornelius Hopper and Otto Sartorius awards for excellence in breast cancer research, and a Fulbright Scholar Award. She was a Distinguished Lecturer for the American Society for Microbiology (2011-13). Her courses at UC Berkeley are Public Health Microbiology (PH162A) and Viruses and Human Cancer (PH266).

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